Galileo
has two key technical advantages. First is its enabling Cell Energy
Discovery Platform that integrates high throughput screening
technologies with both proprietary cell models of human metabolism
and dynamic kinetic assays. This platform expedites identifying metabolic
nutritional and pharmaceutical targets and enables lead identification
and optimization. Second is the Company's novel medicinal chemistry
effort directed towards fundamentally new classes of compounds.
Galileo's
proprietary cell lines accurately model human metabolism at various
organ sites in the body. Using these realistic models, Galileo can
identify points of metabolic vulnerability and the prophylactic
or therapeutic impact of product candidates. These proprietary models,
called Energetically Competent cell lines (EC2),
are unique inasmuch as they model vital organs metabolism.
Galileo's
Energetically Competent cell lines accurately model human
metabolism, dramatically improving our ability to qualify bioactive
candidates that can prevent or treat metabolic and oxidative stress.
At
the core of Galileo's research and development program is its proprietary
Cell Energy Discovery Platform. This platform successfully
links Galileo's EC2 cell lines with assays and robotic technologies
to create an integrated system that allows millions of diverse potential
nutritional and pharmaceutical compositions to be evaluated
for beneficial properties.
Galileo
has an extensive portfolio of proprietary natural products and synthetic
compositions in various stages of development for its nutritional
and pharmaceutical development programs. Galileo has several
nutritional product candidates in or about to enter clinical trials
targeting the inflammatory components of cardiovascular disease,
perimenopausal dyscrasias, and renal failure. In its heart attack
and stroke pharmaceutical programs, Galileo will use human bioactivity
data and biomarker response profiles from its clinical nutrition
programs in conjunction with preclinical pharma data and will complete
analogues and PKADME/tox to underpin an IND filing.