Galileo
couples proprietary cell-based functional models of human metabolism
with novel charge-transfer chemistry, enabling the identification
of unique synthetic pharmacophores for disease treatment and of
bioactive nutraphores for disease prevention and management.
Galileo
is a fundamentally unique enterprise in both its pursuit of metabolic
clinical targets and its combined pharma-nutrition development platform.
Using a single R&D platform carries significant advantages
including cost-effective human therapeutic target validation and
early revenue.
Galileo's
nutrition product strategy is to create proprietary, clinically
proved products containing condition-specific Nutrient Ingredient
Systems for at-risk healthy consumers and select affected-patient
populations and to commercialize them through market leaders.
The
pharmaceutical discovery program at Galileo utilizes as a platform
the fundamentals of metabolic physiology. Unlike programs that are
standard to the pharmaceutical industry, Galileo utilizes high throughput
screening technology to identify new chemical entities that fundamentally
protect sensitive metabolically active cells from oxidative and
metabolic stress.
Using
this functional target approach (as opposed to the classic structural
target approach) to drug discovery, Galileo has succeeded in rapidly
identifying novel compounds for potential development as anti-ischemic
and anti-inflammatory therapies for stroke and myocardial infarction.
Because Galileo's new compound classes are originally derived from
bioactive product libraries, the risk of significant preclinical
safety issues is mitigated. Additionally, development programs on
parallel bioactive nutritionals can effectively mitigate clinical
safety and efficacy risks that are normally inherent to pharmaceutical
development.
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