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Phenergan with codeine vs tussionex or morphine without codeine. In our previous review [22,
compazine vs phenergan allergy 23] we compared the efficacy of codeine with or without morphine in the management of acute urinary retention. In this study we compared the effectiveness of codeine with or without tussionex morphine in the management of acute urinary retention.
METHODS AND SETTING:
This was a retrospective study in seven university centres Switzerland. Participants were included if they admitted with acute urinary retention, had a serum creatinine level below 10 mg/L, had previous urinary retention history, were prescribed codeine for non-neoplastic, non-nebrovascular, or refractory complaints and had not received codeine for at least 5 years. All participants were treated in the ED during first 4 h; in all except one hospital, the study was double blind.
FINDINGS:
A total of 1,933 patients were included: 822 males and 721 females. The median age was 47.9, 58.0% of participants were female and 75.0% white. Codeine or tussionex were used by 76.8% of patients in the tussionex group and 70.0% in the morphine group (p = 0.0039) (data not shown). Patients in the codeine group had better recovery in ICU days 1, 2 and 3, whereas there were no differences in improvement between groups. The treatment effect disappeared after 6 days of treatment. Codeine was associated with increased frequency of ICU admission (p < 0.03), longer stay in the ICU (p < 0.01), and higher mortality in those admitted (p < 0.001) [21,24-26]. Codeine was associated with higher serum creatinine levels (p = 0.0038) and higher mortality in patients treated with tussionex (p = 0.0065) (data not shown).
INTERPRETATION:
The results indicate that codeine without morphine should be the first-line medication for those with acute urinary canada pharmacy store online retention and can cause more severe mortality in those with refractory urinary retention syndrome. In addition, tussionex is superior to codeine [21,24,27].
FUNDING:
Fonds National de la Recherche Scientifique.
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On Wednesday, the legislature's finance committee approved a bill that would require water utility companies to buy their treated water in bulk.
The government says that will ensure the province's clean drinking water supply is protected.
The committee heard from nearly two dozen Nova Scotia representatives, including some from the municipal sector.
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The bill will probably get a third reading by the legislature's finance committee on Jan. 25.
Other water law amendments made by the committee would also ensure that homeowners can take short showers and still be charged for water they use "hot heating" and "bathtub heating."
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On Friday, the Washington Post reported that in a private lunch meeting next week, the presumptive Republican nominee "blatantly admitted that the party he wants to lead is not the one on table today—and that he doesn't support the ones who are."
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